Pre-Menopausal Lipid Profile May Predict Risk of Stroke in Post-Menopausal Women

avatarby Platinum NaturalsLast updated Nov 2, 2017Category: Hot Topics

More than 1 in 3 women have some form of cardiovascular disease. Cardiovascular disease is the number one killer of women in North America (Wellons et al., 2012).

STUDY PARTICULARS

  • 863 post-menopausal women with no history of heart attack or stroke underwent carotid ultrasound scans at follow-up year 12 or 13 to measure presence and size of carotid plaques.

LIMITS OF THIS STUDY

  • Changes in lesion size in relation to changes in lipids around the final menstrual period could not be made because only a single post-menopausal measurement was made.

WHAT WAS ALREADY KNOWN

  • An increase in heart attacks and strokes among women is seen about 10 years after menopause (average age of menopause onset is age 54) (Appiah et al.,2016).
  • The risk of heart disease and stroke is doubled for women who go into early menopause, regardless of ethnicity.

WHAT THIS STUDY ADDS

  • The greater and faster the changes in lipid profile experienced by pre-menopausal women, the greater their risk of significant carotid plaque formation (size and number).
  • Monitoring lipid profile earlier and more frequently during pre-menopause may reduce the risk of heart disease and stroke.
  • Diet and exercise intervention in midlife women led to significant beneficial improvements in risk factors, including lipid profile and LDL cholesterol.
  • Early surveillance together with lifestyle changes may slow the progression of carotid plaques amongst pre-menopausal and post-menopausal women.

HEART HEALTH BEFORE AND AFTER MENOPAUSE

  • Clinical studies have shown that CoQ10, Vitamin C and E, grape seed extract, green tea extract, hawthorn, and omega-3 fatty acids work to help maintain and support a healthy cardiovascular system.
  • Together, these natural ingredients help to maintain a healthy lipid profile and may reduce the size of atherogenic
    and carotid plaques.

Matthews, K.A., El Khoudary, S.R., Brooks, M.M., Derby, C.A., Harlow, S.D., Barinas-Mitchell, E.J.M. and Thurston, R.C. (2017) Lipid changes around the final menstrual period predict carotid subclinical disease in postmenopausal women. Stroke 48: 70-76.

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